Largepox is a rare Sorcery card from Mystery Booster Playtest Cards 2021 (CMB2), collector number 44. Current market price: $0.29, TCGplayer market prices via Scryfall.
Each player discards a card, then loses 1 life, then sacrifices an artifact, a creature, an enchantment, a land, a planeswalker, and a tribal permanent, then exiles a card from their graveyard, then puts the top card of their library into their graveyard, then removes a counter from a permanent they control, then gets a poison counter.